Cambridge Research Biochemicals purchases high quality Fmoc-protected amino acids already stable-isotopically labelled from Cambridge Isotope Laboratory (CIL) through its UK distributor Goss Scientific.
A list of ubiquitously labelled (13C, 15N) amino acids which can be incorporated into peptides is shown below. The least expensive and most convenient to use are towards the top of the list.
| Amino acid | Mass increase |
|---|---|
| Leu | 7 |
| Val | 6 |
| Phe | 10 |
| Pro | 6 |
| Gly | 3 |
| Ala | 4 |
| Ile | 7 |
| Ser | 4 |
| Tyr | 10 |
| Asn | 5 |
| Met | 6 |
| Lys | 8 |
| Gln | 6 |
| Arg | 10 |
| Cys | 4 |
| Glu | 4 |
| Thr | 5 |
| Trp | 13 |
At present, we are unable to supply peptides containing ubiquitously labelled Asp and His. A number of other stable labelled amino acids can be used – please enquire for details.