A highly specific antibody to Cache Valley Virus

Posted by & filed under Antibodies, Blog, Case Studies: Customer's publication, Discovery Antibodies, News, TARGET Antibodies: Polyclonal Antibody Production.

Alain Kohl’s team at the MRC-University of Glasgow Centre for Virus Research chose to recruit the technical expertise of Cambridge Research Biochemicals (CRB) to raise custom polyclonal antibodies specific to the mosquito born Peribunyaviridae family virus; Cache Valley virus (CVV) as well as to Kairi-virus (KRIV). CVV has a tri-segmented, single-stranded genome with negative or ambi-sense polarity which encode… Read more »

Histone mutations play important roles in DNA organisation

Posted by & filed under Antibodies, Blog, Discovery Antibodies, Post-Translational Modifications, TARGET Antibodies: Polyclonal Antibody Production.

Discovery antibodies a select set of catalogue antibodies

Histone proteins help compact and organise the DNA of the nucleus, they also play key roles in orchestrating gene expression. The four core histones, H2A, H2B, H3 and H4 form a complex around which DNA is wound forming the nucleosome. Between the nucleosome is the internucleosomal DNA which is stabilised by the linker histone H1. Modifications of histones can alter the nature… Read more »